CANSSI Ontario STAGE

Trainees and Alumni

Trainees

STAGE Trainees are the graduate students and postdoctoral fellows who are active in the program.

MentorsAffliliation(s)Project Title
Term

(Start and Expected Completion)

PhD Students

Gengming HeLisa Strug (primary)University of Toronto, Dalla Lana School of Public Health, Division of BiostatisticsInvestigating human nasal epithelia as a respiratory model for Cystic Fibrosis using RNA-SequencingSep 2020 - Aug 2022

Sangook Kim
Lisa Strug (primary)
Shelley Bull
Johanna Rommens
Anne Stephenson
University of Toronto, Dalla Lana School of Public Health and The Hospital for Sick ChildrenDevelopment of a phenotype for Lung Disease in Cystic Fibrosis: applications to genetic association across cohorts and countriesNov 2017

Michael Lebenbaum
France Gagnon (primary)
Laurent Briollais
University of Toronto
Dalla Lana School of Public Health and the Institute of Health Policy, Management and Evaluation
Genetic endowments and social capital: An examination of the association between Polygenic scores for educational attainment and adult social capitalSep 2020 - Aug 2022
Yu-Chung (Jerry) LinLisa Strug (primary)
Lei Sun
Johanna Rommens
University of Toronto, Dalla Lana School of Public Health, Division of BiostatisticsIncorporating Robust Statistical Procedures into Model Selection Using Genomic Features with Small Effect SizesSep 2020 - Aug 2022

Victoria Marshe
James Kennedy (primary)
Anna Goldenberg
Andrew Paterson
University of Toronto, Institute of Medical Sciences, Centre for Addiction and Mental HealthApplying machine learning to genomic data to identify diagnostic subtypes in late-life depressionSep 2016
Fan WangLisa Strug (primary)
Lei Sun
Johanna Rommens
The Hospital for Sick ChildrenCo-localization Method with Application in Cystic FibrosisSep 2020 - Aug 2022
Changchang XuShelley Bull (primary)
Irene Andrulis
University of Toronto, Dalla Lana School of Public Health, Division of BiostatisticsImproving mixture cure modelling of multiple molecular factors in cancer prognosisSep 2020 - Aug 2022

Dongyang Yang
Wei Xu (primary)
Andrew Paterson
Geoffrey Liu
University of Toronto, Dalla Lana School of Public Health, Division of BiostatisticsPartition of Human Microbiome Sequencing Data and Analysis of genome-wide Genetic Association through a
Distance-based Unsupervised Learning Model
Sep 2020 - Aug 2022

Lin Zhang
Lei Sun (primary)
Lisa Strug
Johanna Rommens
University of Toronto
Department of Statistical Sciences
A robust and unifying regression framework for allele-based association testDec 2017 - TBD
Yanyan ZhaoLei Sun (primary)
Lisa Strug
Johanna Rommens
University of Toronto, Department of Statistical SciencesA unified regression framework for polygenic risk score, PrediXcan, and TWAS tests Dec 2017 - TBD

Postdoctoral Fellows

MentorsAffliliation(s)Project Title
Term

(Start and Expected Completion)


Myriam Brossard
Shelley Bull (primary)
Radu Craiu
Rayjean Hung
Lunenfeld-Tanenbaum Research InstituteDevelopment of novel statistical methods for genetic analysis of complex traitsDec 2017 - Nov 2019

Kexin Luo
Shelley Bull (primary)
Andrew Paterson
Irene Andrulis
Lunenfeld-Tanenbaum Research InstituteStatistical methods for region-based genome-wide association study (GWAS) analysis of common and rarevariantsSep 2020 - Aug 2022

Elham Khodayari Moez
Rayjean Hung (primary)
Stephen Lye
Lisa Strug
Lunenfeld-Tanenbaum Research InstituteInvestigating host genomics and epigenomics for early childhood cytomegalovirus sequelae based on birth cohortSep 2020 - Aug 2022
Divya SharmaWei Xu (primary)
Andrew Paterson
Geoffrey Liu
University of Toronto, Dalla Lana School of Public Health, Division of Biostatistics Application of machine learning in longitudinal microbiome data analysis for disease predictionSep 2020 - Aug 2022
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Alumni

STAGE Alumni are the graduate students, postdoctoral fellows, and visiting scholars who have participated in the program over the years.

Master's Student

MentorsSTAGE Project Title and AffiliationTraining Dates

Current Position

Tabitha Kung
France Gagnon (primary) and Katherine Siminovitch (ad hoc)Genetic Predictors of Response to Treatment in Early Rheumatoid Arthritis

University of Toronto Dalla Lana School of Public Health, Division of Epidemiology
May 2011 - Jun 2012Assistant Professor in the Department of Medicine at Queen's University and Clinician-scientist at KGH Research Institute (2021)

PhD Students

MentorsSTAGE Project Title and AffiliationTraining DatesCurrent Position

Darren Brenner
Shelley B. Bull
Rayjean Hung (primary)
Geoffrey Liu
A histology specific genome-wide investigation of lung cancer

University of Toronto Dalla Lana School of Public Health, Division of Epidemiology
Jan 2011 - Jun 2012Assistant Professor, University of Calgary (2021)
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Jessica Dennis
France Gagnon (primary)
Zdenka Pausova
Lisa Strug
Genetic and epigenetic factors in the regulation of tissue factor pathway inhibitor (TFPI) plasma levels and role in venous thromboembolism


University of Toronto Dalla Lana School of Public Health, Division of Epidemiology
Oct 2011 - Jan 2016Assistant Professor, Department of Medical Genetics at UBC and Investigator at BC Children's Hospital Research Institute (2021)

Andriy Derkach
Andrew Paterson
Johanna Rommens
Lei Sun (primary)
Jerry Lawless
Statistical methodologies for genetic association studies with rare variants

University of Toronto,
Department of Statistical Sciences
Jan 2011 - Jun 2014Assistant Attending, Department of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center (2021)

Osvaldo Espin-Garcia
Shellley Bull (primary)
Wei Xu
Andrew Paterson
Geoffrey Liu
Integrative methods for design and analysis of genetic association studies


University of Toronto Dalla Lana School of Public Health, Division of Biostatistics, and
Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital
Sep 2016 - Aug 2018Assistant Professor, Biostatistics Division, Dalla Lana School of Public Health, University of Toronto (2021)

Karl Everett
France Gagnon (primary)
Michael Wilson
Genetic and epigenetic determinants of apolipoproteins B and A1 plasma levels and their associations with hypercoagulabilitySep 2016 - Aug 2017

Laura Faye
Shelley B. Bull (primary)
Lei Sun
Accurate and efficient estimation of genetic effect in genome-wide association and genetic sequencing studies.

University of Toronto Dalla Lana School of Public Health, Division of Biostatistics
Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital
Jan 2011 - Jul 2013Senior Researcher at the Canadian Institute for Health Information (CIHI) (2021)

Sarah Gagliano
Jo Knight (primary)
Andrew Paterson
Cathy Barr
Identification of risk variants in genome-wide association studies using functional characteristics

University of Toronto Institute of Medical Science, and
Centre for Addiction and Mental Health, Neuroscience Research Department
Sep 2014 - Nov 2015Assistant Professor, Université de Montréal, Department of Medicine and Department of Neurosciences, Montreal Heart Institute (from July 2020).

Linda Kachuri
Rayjean Hung (primary)
Lei Sun
Geoffrey LIu
Comprehensive investigation of telomere length and its genetic determinants in cancer risk and clinical outcomes.Sep 2014 - Aug 2016Post-doctoral fellow at University of California - San Francisco (2021)
Michael LerroFrance Gagnon (primary)
Michael Wilson
Epistatic mechanisms dictating the thrombotic risk factor endogenous thrombin potential

University of Toronto Dalla Lana School of Public Health, Division of Epidemiology
Sep 2016 - Aug 2020

Weili Li
Lisa Strug (primary)
Johanna Rommens
Rayjean Hung
Developing novel statistical methods under the evidential framework with a focus on analyzing sequence data

University of Toronto Dalla Lana School of Public Health, Division of Biostatistics
Oct 2011 - Aug 2015Manager of The Centre for Applied Genomics (TCAG) statistical genetics facility (2021)

Dave Soave
Lei Sun (primary)
Lisa Strug
Johanna Rommens
Predicting cystic fibrosis-related diabetes using longitudinal measures of pancreatic damage from birth for better patient managementFeb 2013 - Aug 2016Assistant Professor, Wilfrid Laurier University (2021)

Matthew Warkentin
Rayjean Hung (primary)
Geoffrey Liu
Laurent Briollais
University of Toronto Dalla Lana School of Public Health
Lunenfeld-Tanenbaum Research Institute
Improving lung cancer risk prediction using an epidemiologic, genomic, and radiomic approachPhD Candidate in Epidemiology at Dalla Lana School of Public Health at the University of Toronto (2021)

Jingxiong (Amelia) Xu
Laurent Briollais (primary)
Wei Xu
Stephen Lye
Rayjean Hung
Analysis of genome-wide G by E interaction studies through Bayesian graphical modelingSept 2014 - Aug 2016PhD in progress (2021)

Nora Zwingerman
France Gagnon (primary)
Zdenka Pausova
Matthieu Lemire
The association of DNA variants and DNA methylation levels with fibrinolytic protein levelsJul 2013 - Aug 2015PhD in progress

Postdoctoral Fellows

MentorsSTAGE Project Title and AffiliationTraining DatesCurrent Position

Christie Burton
Paul Arnold
Andrew Paterson
Lisa Strug (primary)
Examining the possible role of dopamine and glutamate gene networks in response to inhibition to understand the genetics of Attention Deficit/Hyperactivity Disorder

The Hospital for Sick Children
Feb 2013 - Jan 2015Postdoctoral Research Fellow at The Hospital for Sick Children (2021)

Zhijian (Charlie) Chen
Shelley B. Bull (primary)
Radu Craiu
Andrew Paterson
Design and analysis of genome-wide studies of complex diseases and traits.

Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital
Jan 2011 - Aug 2013Manager, Model Validation and Approval, Bank of Nova Scotia (2013)

Elizabeth Corfield
Lisa Strug (primary)
Andrew Paterson
Anne Bassett
Characterizing the genetics of ADHD traits with cognitive deficits in a pediatric community-based sample

The Hospital for Sick Children
Dec 2017 - Nov 2018Researcher, Norwegian Institute of Public Health (2021)

Eileen Crowley
Andrew Paterson (primary)
Lisa Strug
Whole exome sequencing of veo-IBD patients from the NEOPICS International Cohort Study

The Hospital for Sick Children
Jul 2018 - Jun 2019Pediatric Gastroenterologist, Clinician Researcher in Pediatric IBD at London Heath Sciences Centre (LHSC) and Assistant Professor, Western University. (2021)
Robbie (Robert) DaviesStephen Scherer (primary)
Andrew Paterson
Lisa Strug
Using genetic variants across the allele frequency spectrum to study autism spectrum disorder

The Hospital for Sick Children
Jun 2018 - Jul 2019Associate Professor of Statistical and Population Genomics, University of Oxford (2021)

Gord Fehringer
Laurent Briollais
Rayjean Hung (primary)
Geoffrey Liu
Genome-wide and post genome-wide studies of lung cancer and head and neck cancerJan 2011 - Jan 2012Linkage Analyst at Institute for Clinical Evaluative Sciences (ICES) (2021)

Linda Hiraki
Shelley Bull
Andrew Paterson (primary)
Zdenka Pausova
Identification of genetic variants associated with renal function in type 1 diabetes.

The Hospital for Sick Children
Jul 2013 - June 2015Staff Physician, Division of Rheumatology, Scientist, Genetics & Genome Biology, SickKids and Assistant Professor in the Dalla Lana School of Public Heath at the University of Toronto (2021)

Yue (Cindy) Jiang
Jayne Danska (primary)
Andrew Paterson
Lisa Strug
A systems based analytical framework for metatranscriptomic studies of type 1 diabetes

The Hospital for Sick Children
Sep 2012 - Aug 2015

Sareh Keshavarzi
Andrew Paterson (primary)
France Gagnon
Angelo Canty
Multivariate meta genome-wide association of cardiovascular disease risk factors in Type 1 diabetes

The Hospital for Sick Children
Sep 2016 - Aug 2018Postdoctoral Fellow, The Hospital for Sick Children

Agnieszka Krol
Laurent Briollais (primary)
Development of multistate models for rare variant analysis in familial cancer studies

Lunenfeld-Tanenbaum Research Institute
Jul 2017 - Nov 2017Postdoctoral Fellow, AstraZeneca (2021)

Martin Ladouceur
France Gagnon (primary)
Mathieu Lemire
Arturas Petronis
Statistical models to characterize genome-wide DNA methylation from multigenerational families

University of Toronto
Nov 2012 - Dec 2013Director of Statistics, Senior Research Scientist, Real-World Evidence at Evidera and Adjunct Clinical Professor at Université de Montréal (2021)

Alejandra E. Medina Rivera
France Gagnon
Jo Knight
Michael Wilson (primary)
Leveraging functional genomics data to enhance GWAS analyses and causal variant identification

The Hospital for Sick Children
Sep 2014 - Mar 2015Research associate at the International Laboratory for Human Genomics, National University of Mexico (2021)

Melissa Miller
France Gagnon
Lisa Strug (primary)
Johanna Rommens
Identifying Genetic Modifiers of Immunoreactive Trypsinogen Levels in a NBS Population in Cystic Fibrosis

The Hospital for Sick Children
Mar 2011-Feb 2014Director of Human Genetics, Internal Medicine Research Unit, Pfizer (2021)
Saira MirzaJoanne Knight (primary)
The association between genetic and imaging markers of neurodegeneration across dementias-A data-driven approach

Sunnybrook Health Sciences Centre
Sep 2016 - Aug 2018Clinical Research Associate at Sunnybrook (2021)

Vanessa Oliveira
James L. Kennedy (primary)
Andrew Paterson
Lei Sun
Variability of the DRD4 gene in behavioural phenotypes

Centre for Addiction and Mental Health
Sep 2011 - Aug 2013Scientist, Centre for Addiction and Mental Health and Assistant Professor, Department of Psychiatry, University of Toronto (2021)

Marie Pigeyre
Guillaume Paré (primary)Identification of novel biomarkers to predict vascular complications of Type 2 diabetes: A Mendelian Randomization approach

McMaster University, Department of Pathology and Molecular Medicine
Dec 2017 - Jun 2019Assistant Professor of Medicine, McMaster University (2021)
Razvan RomanescuShelley Bull (primary)
Irene Andrulis
Julia Knight
Pathway-based detection of rare mutations in affected relatives

Lunenfeld-Tanenbaum Research Institute
Dec 2017 - Jan 2020Biostatistical Consultant at George and Fay Yee Centre for Healthcare Innovation and Assistant Professor at the University of Manitoba (2021)

Delnaz Roshandel
Andrew Paterson (primary)
Shelley Bull
Michael Wilson
Genetics of skin fluorescence: an indicator of long term diabetes complicationsSep 2014 - Aug 2016Senior Bioinformatician, The Hospital for Sick Children (2021)
Fodé TounkaraLaurent Briollais (primary)
Julia Knight
Extending risk prediction models for hereditary breast ovarian cancer (HBOC) families

Lunenfeld-Tanenbaum Research Institute
Jul 2018 - Dec 2018Assistant Professor, Department of Statistics, University of Toronto (2021)

Yan Yan Wu
Laurent Briollais (primary)
Julia Knight
Stephen J. Lye
Development of statistical methods for BMI growth curves estimation and analysis on longitudinal GWAS data in relation to metabolic traits in children

Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital
Aug 2012 - Aug 2014Associate Professor,
Office of Public Health Studies,
University of Hawaii at Manoa (2021)

Lizhen Xu
Wei Xu (primary)
Andrew Paterson
Latent variable modeling of longitudinal family microbiome data

University of Toronto Dalla Lana School of Public Health
Jul 2013 - Oct 2014Senior Biostatistician, People Health Research Institute, McMaster University (2021)

Yildiz Yilmaz
Irene L. Andrulis
Shelley B. Bull (primary)
Julia Knight
Statistical methods for molecular genetic analysis of breast cancer

Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital
Jan 2011 - May 2013Associate Professor of Statistics at Memorial University of Newfoundland (2021)

Visiting Faculty

MentorsSTAGE Project Title and AffiliationTraining DatesCurrent Position

Hance Clarke
Jo Knight (primary)
Andrew Paterson
Michael Wilson
Chronic post surgical pain - A pilot genome-wide association study.

University of Toronto Faculty of Medicine and University Health Network
Jul 2013 - July 2014Director of Pain Services and the medical director of the Pain Research Unit at the Toronto General Hospital. Associate Professor in the Department of Anesthesiology & Pain Medicine at University of Toronto (2021)

Sara Good
Andrew Paterson (primary)
Angelo Canty
Michael Wilson
Using imputed gene expression values to look for genetic risk factors associated with complications of Type 1 diabetesJan 2017 - Dec 2017Associate Professor, University of Winnipeg (2021)

Marc Woodbury-Smith
Andrew Paterson (primary)
Stephen Scherer
Lei Sun
Identifying functional rare variants in autism spectrum disorders (ASD) families

McMaster University
Jan 2012 - Dec 2013Clinical Senior Lecturer/Hon Consultant in the Faculty of Medical Sciences at Newcastle University (2021)