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X-WR-CALNAME:CANSSI Ontario STAGE
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UID:MEC-cfa3a0bc94975cb9c346a585ccb3ad9e@stage.utoronto.ca
DTSTART:20170303T170000Z
DTEND:20170303T180000Z
DTSTAMP:20250624T225600Z
CREATED:20250624
LAST-MODIFIED:20260316
PRIORITY:5
SEQUENCE:105
TRANSP:OPAQUE
SUMMARY:STAGE ISSS: Joanna Biernacka
DESCRIPTION:\nJoin us for the next instalment of the STAGE International Speaker Seminar Series (ISSS) with\n\n\n\nJoanna Biernacka\n\n\n\nDirector of Psychiatric Genomics and Pharmacogenomics Program,Professor of Biostatistics, Mayo Clinic College of Medicine and Science\n\n\n\nTalk Title:\n\n\n\nPsychiatric Genomics and Pharmacogenomics: Recent Advances and Ongoing Challenges\n\n\n\nAbstract:\n\n\n\nGenetic studies completed over the past decade have identified numerous genetic variants contributing to common psychiatric traits. However, despite high overall trait heritability of diseases such as bipolar disorder, risk variants identified thus far explain a relatively small proportion of variation in these traits. Furthermore, recent studies have demonstrated a very high level of polygenicity underlying many psychiatric conditions, which poses considerable challenges for risk gene identification and risk prediction. These observations reveal the difficulties facing the implementation of precision medicine in psychiatry. The high polygenicity of psychiatric traits is believed to be driven partly by a high degree of underlying clinical and genetic heterogeneity. In this talk I will give examples of analyses that take into account phenotypic heterogeneity to identify genetic risk factors for complex psychiatric traits and to learn about their genetic architecture. I will also discuss the need for development of statistical methods that can address genetic heterogeneity in studies of complex traits, both in the search for contributing risk factors and in risk prediction.\n\n\n\nSpeaker Profile:\n\n\n\nUnavailable\n\n\n\nSpeaker Poster:\n\n\n\n\n\n\n\nJoanna Biernacka Poster ( https://stage.utoronto.ca/wp-content/uploads/2025/07/Joanna-Biernacka-seminar.pdf )Download\n\n\n\n\n\n\n\nPhotography Disclosure:\n\n\n\nPhotographs and/or video may be taken of participants at STAGE events. These photos/videos are for the Program’s use only and may appear on its website, in printed brochures, or in other promotional or reporting materials. By attending STAGE events, you accept the possibility that you may be videotaped or photographed. If you have any concerns, please inform us by sending an e-mail to esther.berzunza@utoronto.ca\n
URL:https://stage.utoronto.ca/events/stage-isss-joanna-biernacka/
ORGANIZER;CN=CANSSI Ontario:MAILTO:esther.berzunza@utoronto.ca
CATEGORIES:CANSSI Ontario STAGE ISSS
LOCATION:1st Floor, Black Wing, 555 University Avenue, Toronto, ON
ATTACH;FMTTYPE=image/png:https://stage.utoronto.ca/wp-content/uploads/2025/06/Biernacka-Joanna-e1681504968348.png
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