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X-WR-CALNAME:CANSSI Ontario STAGE
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DTSTART:20201204T170000Z
DTEND:20201204T180000Z
DTSTAMP:20230306T204700Z
CREATED:20230306
LAST-MODIFIED:20260316
PRIORITY:5
SEQUENCE:21
TRANSP:OPAQUE
SUMMARY:STAGE ISSS: Kathryn Roeder
DESCRIPTION:\nJoin us for the next instalment of the STAGE International Speaker Seminar Series (ISSS) with\n\n\n\nDr. Kathryn Roeder\n\n\n\nUPMC Professor Statistics and Life SciencesDepartment of Statistics and Data ScienceCarnegie Mellon University\n\n\n\nTalk Title\n\n\n\nStatistics and Genetics Offer a Window into Autism\n\n\n\nAbstract\n\n\n\nRecently the largest exome sequencing study to date of autism spectrum disorder (ASD) implicated 102 genes in risk. An innovative statistical approach was required to obtain this breakthrough for a disorder that has been unusually challenging to unravel.   This risk gene set serves as a springboard for additional explorations into the etiological pathways of ASD, which can guide in the hunt for therapeutics.  Quantification of gene expression, both single cell and bulk RNA-sequencing of brain tissues, can be a critical step in such investigations.   We describe our statistical approaches to understand how cells develop in the brain, identifying both when and where these risk genes are primarily active.  Together, our methods and results can broaden our understanding of the neurobiology of ASD.\n\n\n\nSpeaker Profile\n\n\n\nKathryn Roeder is the UPMC Professor of Statistics and Life Sciences in the Departments of Statistics and Data Science and Computational Biology.  Dr. Roeder has developed statistical and machine learning methods in a wide spectrum of areas, including high dimensional data problems in genetics.  Her work focuses on statistical methods to reveal the genetic basis of complex disease.  She is one of the leaders of the Autism Sequencing Consortium, an international organization dedicated to discovering the genetic etiology of autism.  She received the Committee of Presidents of Statistical Societies (COPSS) Presidents’ Award (1997), Snedecor Award for outstanding work in statistical applications (1997) and Distinguished Achievement Award and Lectureship (2020). She is an elected fellow of the American Statistical Association, the Institute of Mathematical Statistics and AAAS.  In 2019 she was elected to the National Academy of Sciences.\n\n\n\nSponsors\n\n\n\nCANSSI Ontario STAGE (STAGE) is a training program in genetic epidemiology and statistical genetics housed at the University of Toronto Dalla Lana School of Public Health. It operates with financial and in-kind support from CANSSI Ontario, an extra-departmental unit in the Faculty of Arts & Science at U of T.\n\n\n\nSTAGE would like to thank our generous seminar sponsors!For a complete list of sponsors, please see here ( https://stage.utoronto.ca/sponsors/ ).\n\n\n\nPhotography Disclosure\n\n\n\nPhotographs and/or video may be taken of participants at STAGE events. These photos/videos are for the Program’s use only and may appear on its website, in printed brochures, or in other promotional or reporting materials. By attending STAGE events, you accept the possibility that you may be videotaped or photographed. If you have any concerns, please inform us by sending an e-mail to esther.berzunza@utoronto.ca\n
URL:https://stage.utoronto.ca/events/stage-isss-roeder-kathryn/
CATEGORIES:CANSSI Ontario STAGE ISSS
LOCATION:Zoom (Live Stream)
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