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UID:MEC-b282d1735283e8eea45bce393cefe265@stage.utoronto.ca
DTSTART:20140131T170000Z
DTEND:20140131T180000Z
DTSTAMP:20250721T190300Z
CREATED:20250721
LAST-MODIFIED:20260316
PRIORITY:5
SEQUENCE:110
TRANSP:OPAQUE
SUMMARY:STAGE ISSS: Erwin Schurr
DESCRIPTION:\nJoin us for the next instalment of the STAGE International Speaker Seminar Series (ISSS) with\n\n\n\nErwin Schurr\n\n\n\nJames McGill ProfessorMcGill International TB CentreDepartments of Human Genetics and MedicineMcGill University Infection and Immunity in Global HealthThe Research Institute of the McGill University Health Centre\n\n\n\nTalk Title:\n\n\n\nGenetic dissection of complex infection phenotypes \n\n\n\nAbstract:\n\n\n\nMycobacteria are among the most medically important human pathogens. Susceptibility to mycobacterial disease and immune responses to mycobacterial infection are strongly heritable human traits. Yet, the genetic underpinnings of variability of the immune response and of variation in susceptibility to mycobacterial disease have been poorly investigated compared to non-infectious diseases of more limited global health importance. Here, I will review part of the genetic epidemiological studies that have been done to address the problem of susceptibility to infection with Mycobacterium tuberculosis, drawing in particular on our studies in high transmission settings for M. tuberculosis. Using the example of our studies, I will discuss the complexity of phenotype definition for M. tuberculosis infection. By extension to our genetic studies of the mycobacterial diseases tuberculosis and leprosy, I will discuss for two examples, age-at-onset and endo-phenotypes, how proper definition of phenotype has been key for the successful identification of disease susceptibility genes.\n\n\n\nSpeaker Profile:\n\n\n\nDr. Erwin Schurr is a James McGill Professor of Human Genetics and Experimental Medicine at McGill University, Montreal, and a Medical Scientist at the Research Institute of the McGill University Health Centre (RI-MUHC). Dr. Schurr is a recognized pioneer in the field of global health and genetic susceptibility to infection and leads the multi-disciplinary program on “Infection and Immunity in Global Health” at the RI-MUHC. Through multiple large scale genetic epidemiology studies in endemic countries of tuberculosis and leprosy, Dr. Schurr’s research team has identified major genes, proteins and biochemical pathways that determine susceptibility to common human infectious diseases. Dr. Schurr has served on numerous national and international advisory and grant review panels in the field of infection research, and he is one of the organizers of the Annual Canadian Human and Statistical Genetics Meeting.\n\n\n\nSpeaker Poster:\n\n\n\n\n\n\n\nErwin Schurr Poster ( https://stage.utoronto.ca/wp-content/uploads/2025/07/Schurr-Erwin-Poster.pdf )Download\n\n\n\nPhotography Disclosure:\n\n\n\nPhotographs and/or video may be taken of participants at STAGE events. These photos/videos are for the Program’s use only and may appear on its website, in printed brochures, or in other promotional or reporting materials. By attending STAGE events, you accept the possibility that you may be videotaped or photographed. If you have any concerns, please inform us by sending an e-mail to esther.berzunza@utoronto.ca\n
URL:https://stage.utoronto.ca/events/stage-isss-erwin-schurr/
ORGANIZER;CN=CANSSI Ontario:MAILTO:esther.berzunza@utoronto.ca
CATEGORIES:CANSSI Ontario STAGE ISSS
LOCATION:1st Floor, Black Wing, 555 University Avenue, Toronto, ON
ATTACH;FMTTYPE=image/png:https://stage.utoronto.ca/wp-content/uploads/2025/07/Schurr-Erwin.png
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