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Dr. Richard Simon at the CIHR STAGE ISSS
November 7, 2014 @ 12:00 pm - 1:00 pm
The CIHR STAGE International Speaker Seminar Series proudly presents
Dr. Richard Simon
Chief, Biometric Research Branch
Head, Section on Computational and Systems Biology, Division of Cancer Treatment & Diagnosis
National Cancer Institute
Talk title: Development of Predictive Classifiers Based on High Dimensional Data Validation for an Intended Use
Biotechnology has provided whole genome assays that can serve as powerful tools for elucidation of biological mechanisms and development of predictive models. When the number of candidate variables are greater than the number of cases available, special methods are needed for developing and validating useful models and for validating them. This talk will describe some of these methods. The talk will also describe some applications of predictive models in cancer therapeutics and emphasize the importance of identification of intended use early in the development process.
Richard Simon., is Chief of the Biometric Research Branch and head of the Section on Computational and Systems Biology in the Division of Cancer Treatment & Diagnosis of the National Cancer Institute. Dr. Simon holds a doctoral degree in applied mathematics and computer science from Washington University in St. Louis, Mo. He is a fellow of the American Statistical Association and a former member of the Oncologic Drug Advisory Committee of the FDA. He is the architect of BRB Array Tools software and author of Using Genomics in Clinical Trials and Predictive Medicine (Cambridge U. Press 2013). He is the recipient of the 2013 Karl Peace award of the American Statistical Association “for contributions that have played a pivotal role in bridging the gap among statistics, clinical research, and translational medicine to improve human health”.